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H100 vs MI300X: Hardware and Software Buying Guide

Compare H100 and MI300X memory, CUDA and ROCm requirements, OEM systems, and quote terms.

H100 vs MI300X GPU Comparison

H100 and MI300X are different server platforms. The useful comparison is a complete system running the same workload, with current written quotes and support terms.

Key differences

ItemNVIDIA HGX H100 SXMAMD Instinct MI300X
GPU memory80 GB HBM3192 GB HBM3
PlatformHGX SXMOAM / UBB 2.0
Software ecosystemCUDAROCm

NVIDIA publishes the H100 HGX specifications. AMD publishes the MI300X platform specifications.

The MI300X memory capacity can reduce model sharding for some workloads. H100 may fit better when you already use CUDA-specific libraries or an established Hopper fleet. Speed and cost per token require a benchmark on your model, precision, framework, and GPU count.

Questions for a supplier

  • Which OEM server and part numbers are quoted?
  • What are the CPU, RAM, storage, and network configurations?
  • What cooling and rack power does the system require?
  • What support and warranty terms apply?
  • Is the stated lead time backed by allocation for your quantity and destination?

A price per GPU is insufficient for this comparison. Ask for current matched quotes for complete MI300X and H100 systems.

Browse H100 | Browse MI300X | Request a quote